Mycoplasma genitalium is a sexually transmitted organism. The urogenital tract is the primary site of M. genitalium infection but asymptomatic rectal carriage is reported. M. genitalium is responsible for urethritis in men and for cervicitis, pelvic inflammatory disease, preterm birth and spontaneous abortion in women.
Mycoplasma pneumoniae is responsible for community-acquired respiratory tract infections, such as tracheobronchitis and pneumonia, particularly in school-aged children and young adults. These infections occur both endemically and epidemically at 3- to 7-year intervals worldwide. Numerous extra-respiratory manifestations of variable severity have also been associated with M. pneumoniae infections including dermatological manifestations and neurological complications.